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硅元素修饰合成大麻素受体激动剂的代谢路径解析:基于尿液与尸检 ...
本刊推荐:为应对新型合成大麻素受体激动剂(SCRAs)ADMB-3TMS-PrINACA与Cumyl-3TMS-PrINACA在药物检测中因母体化合物快速代谢带来的挑战,本研究综合运用体外肝微粒体(pHLM)、肝细胞(PHH)代谢模型、人体尿液与尸检样本分析,结合LC-QToF-MS与GC-MS技术,系统阐明其 ...
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