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补体 C4 加剧星形胶质细胞介导的神经炎症并促进帕金森病中 α- 突触 ...
【编辑推荐】为探究补体 C4 在帕金森病(PD)中的作用,研究人员以 α- 突触核蛋白预制纤维(α-syn PFF)注射小鼠等为模型,发现 PD 患者及模型小鼠中 C4 水平升高,其通过加剧星形胶质细胞炎症反应等恶化 PD 病理,为 PD 治疗提供新靶点。 帕金森病(Parkinson’s ...
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