The call by Glenn Begley and Lee Ellis to raise standards in preclinical cancer research (Nature 483, 531–533; 2012) is an admirable piece of self-critique that can be extended to all who study and ...

Scientists are discussing the chasm between biomedical scientists' astounding preclinical success and the meager clinical translatability. They also suggest ways that researchers can improve and ...

Daniel Drucker's unofficial laboratory slogan is "I'd rather be third and right, than first and wrong." As a clinician-scientist who has spent 30 years developing new drugs for diabetes, ...

Reproducibility is one of the buzziest terms in science today. After all, science by its nature is not supposed to be a one-and-done affair. But a new paper in Science Translational Medicine argues ...

Contextual factors, such as the race of participants in an experiment or the geography of where the experiment was run, can reduce the likelihood of replicating psychological studies, a team of ...