ProbeLibrary, a fast, specific and flexible format for quantitative real-time PCR, is described. The ProbeLibrary concept is based on the fact that just 90 short probes provide transcriptome-wide ...

With laboratory methods and diagnostics advancing apace, Francesca Lake considers whether PCR is likely to retain its crown as an essential lab method, or whether it could be replaced and consigned to ...

Researchers have developed a light-induced DNA detection method that enables rapid, PCR-free genetic analysis. Their technique offers ultra-sensitive mutation detection in just five minutes, reducing ...

Please give an overview of microsatellite instability (MSI) status and its applications within oncology. Historically Microsatellite Instability (MSI) has been used to screen for Lynch Syndrome, a ...

Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA and RNA. PCR involves the enzymatic amplification of ...